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Reaction of indolylmagnesium bromide and chloromethylpyridines. Synthesis of skatylpyridines and piperidines
Author(s) -
Degraw Joseph I.,
Kennedy Jill G.,
Skinner W. A.
Publication year - 1966
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570030114
Subject(s) - chemistry , bromide , combinatorial chemistry , organic chemistry
The reaction of indolylmagnesium bromide with the 2‐, 3‐, and 4‐chloromethyl‐pyridines is reported. Methods are described for the preparation of 2‐, 3‐ and 4‐skatylpyridine and 2‐, 3‐ and 4‐skatylpiperidine.