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Fused‐ring systems containing 1,2,4‐benzo thiadiazines. II. Reactions of o ‐amino‐n‐hydroxybenzenesulfonamides
Author(s) -
Wei Peter H. L.,
Bell Stanley C.,
Childress Scott J.
Publication year - 1966
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570030101
Subject(s) - benzothiadiazine , chemistry , ring (chemistry) , tricyclic , stereochemistry , benzothiadiazines , medicinal chemistry , organic chemistry , pharmacology , medicine
o‐Amino‐ N ‐hydroxybenzenesulfonamides have been treated with aldehydes to prepare 2‐hydroxy‐1,2,4‐benzothiadiazine 1,1‐dioxides. These products have permitted the fusion of an additional ring to the “b” face of the benzothiadiazine. Analogs of the tricyclic compounds have been made in other ways.