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Pyrazolo [3,4‐b]pyridines and pyrazolo[3′,4′:6,5]pyrido[2,3‐d]pyrimidines
Author(s) -
Cottis Steve G.,
Clarke Priscilla B.,
Tieckelmann Howard
Publication year - 1965
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570020216
Subject(s) - chemistry , methylhydrazine , hydrazine (antidepressant) , pyridine , medicinal chemistry , stereochemistry , pyrimidine , phenylhydrazine , chromatography
3,6‐Diamino‐5‐cyanopyrazolo[3,4‐b]pyridine (III) and 1‐methyl‐3, 6‐diamino‐5‐cyanopyrazolo[3,4‐b]pyridine (IV) were formed by treatment of 2‐amino‐6‐chloro‐3, 5‐dicyanopyridine with hydrazine and methylhydrazine. Pyrazolo[3′,4′:6,5]pyrido[2,3‐d]pyrimidines were formed from IV and from a number of its derivatives.

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