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The chemistry of pyrazine and its derivatives. IX The pyrazylethylation of amines
Author(s) -
Singerman Gary M.,
Levine Robert
Publication year - 1964
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570010310
Subject(s) - chemistry , pyrazine , acetic acid , catalysis , organic chemistry , sodium , medicinal chemistry
A series of pyrazylethylated derivatives of the type C 4 H 3 N 2 CH 2 CH 2 N= has been prepared in high yields by the reactions of vinylpyrazine with amines using methanolic acetic acid or metallic sodium as the catalyst.
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