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The chemistry of triazine derivatives II. The acylation of 2,4,6‐trimethyl‐ s ‐triazine to triazinyl ketones and their facile isomerization to acetamidopyrimidines
Author(s) -
Osborne David R.,
Wieder William T.,
Levine Robert
Publication year - 1964
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570010309
Subject(s) - chemistry , isomerization , acylation , triazine , organic chemistry , medicinal chemistry , catalysis
A series of triazinyl ketones has been prepared by acylating 2,4,6‐trialkyl‐ s ‐triazines and these ketones have been isomerized to 4‐acylamidopyrimidine derivatives. A possible mechanism for this isomerization is suggested.
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