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(Bromodimethylsulfonium) bromide–catalyzed one‐pot three‐component synthesis of imidazo[1,2‐a]pyridines
Author(s) -
Venkatesham R.,
Manjula A.,
Rao B. Vittal
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.518
Subject(s) - chemistry , catalysis , aldehyde , bromide , 2 aminopyridine , component (thermodynamics) , solvent , organic chemistry , combinatorial chemistry , medicinal chemistry , physics , thermodynamics
(Bromodimethylsulfonium) bromide–catalyzed one‐pot multicomponent reaction of 2‐aminopyridine with aromatic aldehyde(s) and TMSCN yielding N ‐benzylidene‐2‐phenylimidazo[1,2‐a]pyridines exclusively has been described. The reaction is solvent free, versatile, and takes significantly short time. J. Heterocyclic Chem., (2011).
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