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Carbene induced rearrangement products from two furoquinolinone scaffolds
Author(s) -
Lindahl KarlFredrik,
Carroll Anthony,
Quinn Ronald J.,
Ripper Justin A.
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.463
Subject(s) - carbenoid , chemistry , carbene , diazo , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , catalysis , rhodium
Novel double CH‐insertion and rearrangement products ( 5 , 6 , and 7 ) were isolated from treatment of 1 or 2 with dimethyl diazomalonate ( 3 ) under dirhodiumtetrakis mediated carbenoid chemistry conditions. A new possible reaction pathway is suggested and discussed. Also other diazo compounds were tested. J. Heterocyclic Chem., (2010).