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Synthesis of new 1,3‐thiazepine derivatives
Author(s) -
Struga Marta,
Kossakowski Jerzy,
Miroslaw Barbara.,
Koziol Anna E.,
Zimniak Andrzej
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.44
Subject(s) - chemistry , thiourea , condensation , nmr spectra database , stereochemistry , medicinal chemistry , computational chemistry , spectral line , organic chemistry , physics , astronomy , thermodynamics
Condensation of thiourea derivatives with 1,4‐dibromobutane gave 1,3‐thiazepine derivatives ( 1a , 1b , 1c − 3a , 3b , 3c ). Elementary analysis, MS and 1 H NMR spectra confirmed the identity of the products. The molecular structure of 2b was determined by an X‐ray analysis. J. Heterocyclic Chem., (2009).