Preparation and evaluation of  antibacterial activity  of some new 1,2,4‐triazole derivatives | Zendy

Arafa W. A. A. | Zendy

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Preparation and evaluation of antibacterial activity of some new 1,2,4‐triazole derivatives

Author(s) -

Arafa W. A. A.

Publication year - 2010

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.431

Subject(s) - chemistry , antibacterial activity , 1,2,4 triazole , carbohydrazide , combinatorial chemistry , triazole , nuclear chemistry , organic chemistry , bacteria , genetics , biology

Cyclizations of 1,5‐diphenyl[1,2,4]triazole‐3‐carbohydrazide 1 and the thiosemicarbazide 2 (derived from 1 by addition to phenylisothiocyanate) under various conditions afforded novel biheterocyclic systems. The newly prepared compounds were screened for their antibacterial activity . The results showed that several of these compounds exhibited significant antibacterial activity . J. Heterocyclic Chem., (2010).

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