Synthesis of methyl 1, 5‐diaryl‐1 H  ‐pyrrole‐2‐carboxylates via acid‐catalyzed ring‐opening/ring‐closure sequence | Zendy

Huang Long | Zendy; Luo Chenghao | Zendy; Xu Panpan | Zendy; Liu Bing | Zendy; Zhang Duntie | Zendy; Zhang Jing | Zendy; Pang Denghong | Zendy; Gong Yuefa | Zendy

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Synthesis of methyl 1, 5‐diaryl‐1 H ‐pyrrole‐2‐carboxylates via acid‐catalyzed ring‐opening/ring‐closure sequence

Author(s) -

Huang Long,

Luo Chenghao,

Xu Panpan,

Liu Bing,

Zhang Duntie,

Zhang Jing,

Pang Denghong,

Gong Yuefa

Publication year - 2021

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.4306

Subject(s) - chemistry , pyrrole , ring (chemistry) , catalysis , closure (psychology) , medicinal chemistry , sequence (biology) , organic chemistry , economics , market economy , biochemistry

A facile synthesis of methyl 1,5‐diaryl‐1 H ‐pyrrole‐2‐carboxylates was reported in this article. Acid‐catalyzed reaction of methyl 2‐aroyl‐1‐phenoxycyclopropanecarboxylates with aromatic amines underwent smoothly to give methyl 1,5‐diaryl‐1 H ‐pyrrole‐2‐carboxylates in high to excellent yields under mild conditions.

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