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Catalyst‐free synthesis of quinazolinones by oxidative cyclization under visible light in the absence of additives
Author(s) -
Yang Jiangnan,
Xie Zongbo,
Chen Zhongsheng,
Jin Liang,
Li Qian,
Le Zhanggao
Publication year - 2021
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.4275
Subject(s) - chemistry , catalysis , oxidative phosphorylation , visible spectrum , combinatorial chemistry , organic chemistry , biochemistry , physics , optoelectronics
A general metal‐free oxidative cyclization route was developed to synthesize quinazolinones under visible light. A series of substituted 2‐aminobenzamides were reacted with aldehydes or ketones to produce the desired quinazolinones in good yields. Most importantly, the reaction did not require excess oxidant or high temperatures.