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Double 1,3‐dipolar cycloaddition of N ‐methyl Azomethine ylide to meta‐Dinitrobenzene annelated with nitrogen aromatic heterocycles
Author(s) -
Bastrakov Maxim A.,
Starosotnikov Alexey M.,
Pechenkin Sergey Yu.,
Kachala Vadim V.,
Glukhov Ivan V.,
Shevelev Svyatoslav A.
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.423
Subject(s) - azomethine ylide , chemistry , cycloaddition , isoindole , 1,3 dipolar cycloaddition , nitrogen , ylide , medicinal chemistry , organic chemistry , catalysis
The 1,3‐dipolar cycloaddition of unstabilized azomethine ylide 1 with meta‐dinitrobenzene fused with nitrogen heterocycles affords the corresponding decahydropyrrolo[3,4‐ e ]isoindole cycloadducts in good yields. This is a first example of [3+2]‐cycloaddition of azomethine ylides to nitroarenes. J. Heterocyclic Chem., (2010).

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