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Preparation of novel symmetrical bistetrazole‐carbazole derivatives through a one‐pot Ugi‐azide reaction
Author(s) -
Rahimi Shahnaz,
Ghandi Mehdi
Publication year - 2021
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.4206
Subject(s) - chemistry , carbazole , tetrazole , azide , nuclear magnetic resonance spectroscopy , proton nmr , combinatorial chemistry , reaction conditions , ugi reaction , organic chemistry , isocyanide , catalysis
A series of new symmetrical tetrazole‐based carbazole derivatives starting from the initially generated 3,6‐diformyl‐ N ‐alkylcarbazoles were successfully synthesized through a one‐pot Ugi‐azide reaction in moderate to high yields. Simplicity, easily accessible chemicals, mild reaction conditions, and fast separation of the products with the formation of bistetrazole‐based carbazole derivatives in one step are some advantages of this method. The structure of the products was characterized and confirmed by using spectroscopic techniques such as 1 H NMR, 13 C NMR, FT‐IR, and MS spectroscopy.