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Iron‐catalyzed tandem reactions of aldehydes, terminal alkynes, and primary amines as a strategy for the synthesis of quinoline derivatives
Author(s) -
Zhang Yicheng,
Li Pinhua,
Wang Lei
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.417
Subject(s) - chemistry , quinoline , tandem , primary (astronomy) , catalysis , combinatorial chemistry , organic chemistry , condensation , aldehyde , materials science , physics , astronomy , composite material , thermodynamics
FeCl 3 ‐catalyzed three‐component tandem condensation/addition/cyclization/oxidation reactions of aldehydes, terminal alkynes, and primary amines have been developed. The processes can provide a diverse range of quinoline derivatives in good yields from simple starting materials. A possible reaction mechanism was proposed. J. Heterocyclic Chem., (2010).