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Microwave‐assisted Brønsted acidic ionic liquid‐promoted one‐pot synthesis of heterobicyclic dihydropyrimidinones by a three‐component coupling of cyclopentanone, aldehydes, and urea
Author(s) -
Rahman Matiur,
Majee Adinath,
Hajra Alakananda
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.415
Subject(s) - chemistry , cyclopentanone , thiourea , catalysis , ionic liquid , urea , condensation , organic chemistry , component (thermodynamics) , microwave irradiation , solvent , physics , thermodynamics
A simple and efficient method has been developed for the synthesis of heterobicyclic dihydropyrimidinone derivatives through a solvent‐free one‐pot three‐component condensation of aromatic aldehydes, cyclopentanone, and urea or thiourea in the presence of Brønsted acidic ionic liquid under microwave irradiation. The catalyst can be reused at least six times without any noticeable decrease in catalytic activity . J. Heterocyclic Chem., (2010).