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Recent development in the synthesis of pyrrolin‐4‐ones/pyrrolin‐3‐ones
Author(s) -
Sharma Priyanka,
Kumar Rupesh,
Bhargava Gaurav
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.4143
Subject(s) - chemistry , diazo , combinatorial chemistry , organic chemistry
Pyrrolin‐4‐ones/pyrrolin‐3‐ones and its derivatives are important heterocyclic systems which are observed in vast variety of natural products, pharmaceuticals, and biologically important compounds. Different researchers all across the world have developed different synthetic methodologies for the construction of functionalized pyrrolin‐4‐ones/pyrrolin‐3‐one scaffolds such as the transition‐metal catalyzed/mediated cycloisomerizations of 1‐aminoynones and dimerization of enaminones or α‐ diazo ‐β‐ oxoamides etc . The present review article summarizes various reports on the synthesis of various simple and functionalized pyrrolin‐4‐ones/pyrrolin‐3‐ones from 2000 onward.