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Synthesis of a truncated tetradenolide
Author(s) -
Dávila García Álvaro,
Bernès Sylvain,
SartilloPiscil Fernando,
MezaLeón Rosa Luisa
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.4137
Subject(s) - chemistry , enantiopure drug , yield (engineering) , derivative (finance) , lactone , stereochemistry , combinatorial chemistry , organic chemistry , enantioselective synthesis , catalysis , materials science , economics , financial economics , metallurgy
The enantiopure synthesis of a truncated tetradenolide is presented. Starting from the versatile Chiron 7,3‐lactone‐xylofuranose derivative (7,3‐LXF), the enantiomerically pure synthesis of the title compound is obtained in six steps with a 40% overall yield.