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Design, synthesis, and characterization of some novel pyrazolo [1,5‐a] pyrimidines as potent antimicrobial agents
Author(s) -
Dawane Bhaskar S.,
Konda Shankaraiah G.,
Zangade Sainath B.
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.413
Subject(s) - chemistry , antimicrobial , formamide , pyrazole , combinatorial chemistry , thiazole , condensation , organic chemistry , thermodynamics , physics
A novel series of pyrazolo [1,5‐a] pyrimidines were synthesized by the condensation of substituted chalcones with 5‐amino pyrazole in presence of dimethyl formamide. All the synthesized products were characterized by the spectral analysis. Further, all newly synthesized compounds were screened for their antimicrobial activity . Most of the compounds showed potent activity. J. Heterocyclic Chem., (2010).