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Base promoted regioselective aromatization for the preparation of substituted 3‐hydroxybenzene dicarboxylate
Author(s) -
Guo Weihang,
Wang Xianheng,
Zhao Changkuo,
Wang Yuhe
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.4024
Subject(s) - regioselectivity , aromatization , chemistry , base (topology) , phenol , combinatorial chemistry , organic chemistry , catalysis , mathematical analysis , mathematics
A new convenient base promoted aromatization process has been developed to prepare substituted 3‐hydroxybenzene dicarboxylate using commercially available materials. In particular, regioselectivity will occur for substrates with mono‐substitution at 5‐ or 6‐position. This new process provides less reaction steps and moderate yields, and can be used extensively in the synthesis of other substrates to functionalize phenol esters.