Premium
Preparation of 2,5‐disubstituted pyrimidines from vinamidinium salts and synthesis of novel disulfane derivatives
Author(s) -
Rafiee Samani Ziba,
Mehranpour Abdolmohammad,
Hasaninejad Alireza
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3935
Subject(s) - chemistry , thiourea , guanidine , pyrimidine , ethanol , proton nmr , organic chemistry , carbon 13 nmr , stereochemistry
Novel pyrimidine derivatives were prepared from the reaction of 2‐substituted 1,3‐bis(dimethylamino)‐trimethinium salts with thiourea or guanidine in the presence of ethyl‐diisopropylamine in ethanol at reflux, and also some 5‐substituted pyrimidine‐2‐thiols has been used for the synthesis of novel disulfane compounds. Infrared, 1 H NMR, 13 C NMR, and mass spectral data confirm the molecular structures of the newly synthesized compounds. The ultraviolet spectral behavior of these compounds was examined in DMSO and the ƛ max of these compounds was studied.