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Synthesis, antimicrobial activity, and ion transportation investigation of four new [1 + 1] condensed furan and thiophene‐based cycloheterophane amides
Author(s) -
Erkuş Betül,
Özcan Hafize,
Zaim Ömer
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3922
Subject(s) - chemistry , thiophene , bacillus cereus , antimicrobial , furan , candida albicans , escherichia coli , staphylococcus aureus , proton nmr , bacteria , gram , stereochemistry , organic chemistry , microbiology and biotechnology , biochemistry , genetics , gene , biology
Four new macrocyclic compounds with thiophene ( L1 and L2 ) and furan ( L3 and L4 ) rings were synthesized and characterized by IR, 1 H NMR, 13 C NMR, and Q‐TOF spectral data. Macrocyclic amides ( L1 , L2 , L3 , and L4 ) were tested for ion transportation with Na + and K + ions, and also, antimicrobial activities were investigated against the Gram‐negative Escherichia coli ATCC 25922, Gram‐positive Staphylococcus aureus ATCC 25923, Gram‐negative Listeria monocytogenes ATCC 19115, Gram‐negative Salmonella typhimurium ATCC 14028, Bacillus cereus bacteria, and Candida albicans ATCC 10231 for all amides.