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One‐pot synthesis of 2,3‐dihydro‐2‐thioxoquinazolin‐4(1 H )‐ones from nitro‐compounds with the aid of tin(II) chloride
Author(s) -
Wang ManMan,
Dou GuoLan,
Shi DaQing
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.392
Subject(s) - chemistry , tin , nitro , chloride , combinatorial chemistry , medicinal chemistry , organic chemistry , alkyl
A facile synthetic method using SnCl 2 ·2H 2 O system to promote the novel reductive cyclization of 2‐nitrobenzamides and isothiocyanates is described. Sequentially, a series of 2,3‐dihydro‐2‐thioxoquinazolin‐4(1 H )‐ones were synthesized in good yields. J. Heterocyclic Chem., (2010).