Premium
Synthesis of benzo[3,4‐ h ][1,6]naphthyridines via Friedländer condensation with active methylenes
Author(s) -
Rote Ramhari V.,
Bagul Sandeep M.,
Shelar Deepak P.,
Patil Sandeep R.,
Toche Raghunath B.,
Jachak Madhukar N.
Publication year - 2011
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.391
Subject(s) - chemistry , condensation , lithium (medication) , medicinal chemistry , physics , thermodynamics , endocrinology , medicine
Novel 4‐amino‐6‐chloroquinoline‐3‐carbaldehyde has been synthesized by synchronous reduction by lithium aluminiumhydride and finally oxidation with MnO 2 . Friedländer condensation of it with reactive methylenes furnished novel benzo[3,4‐ h ][1,6]naphthyridine derivatives. J. Heterocyclic Chem., (2011).