Premium
A novel catalyst‐free mechanochemical protocol for the synthesis of 2,3‐dihydro‐1 H ‐perimidines
Author(s) -
Harry Nissy Ann,
Radhika Sankaran,
Neetha Mohan,
Anilkumar Gopinathan
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3880
Subject(s) - chemistry , grinding , mortar , catalysis , annulation , organic chemistry , metallurgy , composite material , materials science
A rapid, efficient, and green grinding assisted method for the synthesis of 2,3‐dihydro‐1 H ‐perimidines has been developed. 1,8‐Diaminonaphthalene and aldehydes were ground using mortar and pestle for 5 minutes affording the product in moderate to excellent yields. The methodology minimises the use of conventional workup and column chromatographic techniques.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom