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A novel catalyst‐free mechanochemical protocol for the synthesis of 2,3‐dihydro‐1 H ‐perimidines
Author(s) -
Harry Nissy Ann,
Radhika Sankaran,
Neetha Mohan,
Anilkumar Gopinathan
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3880
Subject(s) - chemistry , grinding , mortar , catalysis , annulation , organic chemistry , metallurgy , composite material , materials science
A rapid, efficient, and green grinding assisted method for the synthesis of 2,3‐dihydro‐1 H ‐perimidines has been developed. 1,8‐Diaminonaphthalene and aldehydes were ground using mortar and pestle for 5 minutes affording the product in moderate to excellent yields. The methodology minimises the use of conventional workup and column chromatographic techniques.