z-logo
Premium
Design and synthesis of diethyl(substituted 2‐benzylbenzofuran‐3‐yl)phosphonates as antioxidant and antimicrobial agents
Author(s) -
Gundluru Mohan,
Sarva Santhisudha,
Sudileti Murali,
Tellamekala Sreekanth,
Yakkate Subba Rao,
Nemallapudi Bakthavatchala Reddy,
Cirandur Suresh Reddy
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3877
Subject(s) - chemistry , antimicrobial , phosphonate , catalysis , dpph , acetylene , ethanol , antioxidant , organic chemistry , bacteria , combinatorial chemistry , genetics , biology
In continuance of our effort to improve novel and potent synthetic approaches for various bioactive phosphorylated heterocycles via C─P bond formation, a series of diethyl substituted(2‐benzylbenzofuran‐3‐yl)phosphonate derivatives ( 4a ‐ j ) was synthesized by one‐pot reaction of various diversely substituted salicylaldehydes, phenyl acetylene, and diethyl phosphite using CuO nanoparticles as catalyst in 1:1 ethanol and water under room temperature. The new compounds have been studied for their radical scavenging activity by DPPH, H 2 O 2 , and NO approaches and antimicrobial activity assay against bacteria and fungi by disk diffusion method.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here