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SO 4 −2 /SnO 2 –catalyzed cyclocondensation for the synthesis of fully functionalized pyridines
Author(s) -
Koduri Ramesh Goud,
Pagadala Ramakanth,
Boodida Sathyanarayana,
Varala Ravi
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3806
Subject(s) - catalysis , chemistry , fourier transform infrared spectroscopy , pyridine , scanning electron microscope , lewis acids and bases , tin , heterogeneous catalysis , tin oxide , nuclear chemistry , oxide , organic chemistry , chemical engineering , materials science , engineering , composite material
An efficient and promising synthetic approach to assemble skeletons of multifunctionalized pyridine derivatives in presence of recyclable heterogeneous sulfated tin oxide (STO) catalyst has been evolved. The STO catalyst was used as a promoter for the cyclocondensation process in ethanol at 70°C. Overall performance of this catalyst was attributed to the cooperative contribution of its Lewis and Brønsted‐Lowry acidic sites. Nanosized STO catalyst was synthesized by using sol‐gel process and characterized by Fourier transform infrared (FTIR) spectroscopy, X‐ray diffraction (XRD), 1 H‐NMR, and scanning electron microscopy (SEM). This catalyst tolerates most of the substrates, and protocol shows precious capabilities consist of high yields, operational simplicity, less reaction time, and eco‐friendly conditions. The newly synthesized heterogeneous catalyst was easily separated and reused. All the reactions are carried out for subsequent cycles without significant loss of catalytic activity and with good proficiency.