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Facile synthesis of 2,6‐diaryl‐4‐secondary aminonicotinonitriles and highly substituted unsymmetrical 2,2′‐bipyridines
Author(s) -
Bhosale Sidhanath V.,
Patil Umesh D.,
Kalyankar Mohan B.,
Nalage Santosh V.,
Patil Vijay S.,
Desale Kamlesh R.
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.380
Subject(s) - chemistry , amidine , yield (engineering) , ring (chemistry) , aryl , transformation (genetics) , combinatorial chemistry , medicinal chemistry , organic chemistry , biochemistry , materials science , alkyl , metallurgy , gene
The ring transformation of 2H ‐pyran‐2‐one by N ‐aryl amidine in the presence of KOH in DMF at room temperature resulted in a facile synthesis of the 2,6‐diaryl‐4‐secondary aminonicotinonitrile and highly substituted unsymmetrical 2,2′‐bipyridines in moderate yield. J. Heterocyclic Chem., (2010).