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Synthesis of 1,2,3 triazole‐linked pyrimidines catalyzed by mg‐Al‐LDH‐immobilized‐CuI as a heterogeneous catalyst
Author(s) -
Rezaeimanesh Fatemeh,
Bakherad Mohammad,
NasrIsfahani Hossein,
Bahramian Bahram,
Naderi Soheila
Publication year - 2020
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3772
Subject(s) - chemistry , catalysis , pyrimidine , click chemistry , triazole , combinatorial chemistry , reaction conditions , nuclear chemistry , organic chemistry , stereochemistry
A useful and efficient procedure was obtained for the synthesis of 1,2,3‐triazole‐linked pyrimidines via click reaction of propynylated pyrimidine and aromatic azides in the presence of Mg‐Al‐LDH‐immobilized‐CuI with high‐to‐excellent yields. Moreover, the prepared catalyst was characterized by the FT‐IR spectroscopy, XRD, BET, SEM, and ICP techniques. The developed synthetic technique offers numerous advantages such as a clean reaction, easy workup, high reaction yields, and short reaction time.