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Synthesis and characterization of active cuprous oxide particles and their catalytic application in 1,2,3‐triazole synthesis via alkyne‐azide cycloaddition reaction in water
Author(s) -
Sawkmie Micky Lanster,
Paul Dipankar,
Kalita Gitumoni,
Agarwala Khushboo,
Maji Pradip K.,
Chatterjee Paresh Nath
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3723
Subject(s) - chemistry , cycloaddition , catalysis , ammonium bromide , oxide , sodium azide , fourier transform infrared spectroscopy , alkyne , bromide , inorganic chemistry , polymer chemistry , nuclear chemistry , organic chemistry , chemical engineering , pulmonary surfactant , biochemistry , engineering
Active cuprous oxide materials are synthesized from CuSO 4 .5H 2 O using sodium stannite as reducing agent in the presence of various stabilizers, viz., cetyl trimethyl ammonium bromide, sodium dodecyl sulphate, and polyvinyl pyrrolidone. The synthesized cuprous oxide materials are well characterized by powder X‐ray diffraction and Fourier transform infrared spectroscopy to ascertain their identity, while field emission scanning electron microscopy and energy‐dispersive spectroscopy analysis were used to study their morphology and composition, respectively. We have compared the catalytic prowess of the various cuprous oxide materials in the cycloaddition reaction of alkynes and azides to synthesize 1,4‐disubstituted‐1,2,3‐triazoles. A wide variety of substitutions can nicely be tolerated in our optimized reaction conditions to produce very good to excellent yields of the corresponding triazoles in water at 55 °C. The reactions are carried out in water without any assistance of organic cosolvent or other additives, which renders the catalytic method as economical and environment friendly.