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Transition‐metal‐free N ‐arylation: A general approach to aza‐fused poly‐heteroaromatics
Author(s) -
Annareddygari Srikanth,
Kasireddy Venkateshwer Reddy,
Reddy Jayachandra
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3722
Subject(s) - chemistry , intramolecular force , intermolecular force , condensation , transition metal , combinatorial chemistry , transformation (genetics) , base (topology) , computational chemistry , organic chemistry , polymer chemistry , stereochemistry , molecule , catalysis , thermodynamics , mathematical analysis , biochemistry , physics , mathematics , gene
A new and efficient method for the synthesis of various aza‐fused poly‐hetero aromatics has been described. This protocol includes an intermolecular condensation followed by metal‐free base‐promoted intramolecular C―N coupling reaction. The advantage of this one‐pot transformation lies in the use of simple cyclic amidines‐like compounds without prefunctionalization of the starting heterocycles.