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Overview on Recent Approaches towards Synthesis of 2‐Keto‐annulated Oxazole Derivatives
Author(s) -
Aljaar Nayyef,
Gujjarappa Raghuram,
AlRefai Mahmoud,
Shtaiwi Majed,
Malakar Chandi C.
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3673
Subject(s) - oxazole , chemistry , combinatorial chemistry , organic chemistry
In recent years, oxazole derivatives have emerged as one of the formidable groups of compounds in the field of medicinal chemistry and drug discovery. The titled compounds 2‐keto‐annulated oxazoles play an important role towards the medicinal aspects. There has been an appearance of a significant number of research articles and reviews to explore the wide utility of oxazole derivatives. However, till now, there has been no dedicated review published focusing on the synthesis of 2‐keto‐annulated oxazole derivatives. Herein, we have presented the recent protocols available in literature for the synthesis of 2‐keto‐annulated oxazoles and highlighted the advantages of these methods that would attract the attention of a broad range of readers in the chemistry community.