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Synthesis of Pyrimidine and Pyran Derivatives with the Related Systems and the Study of Their Behavior in the Liquid Solutions
Author(s) -
ElSayed Refat,
Katouah Hanadi A.
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3607
Subject(s) - chemistry , surface tension , pyran , propylene oxide , reagent , pyrimidine , adsorption , wetting , solubility , organic chemistry , condensation , combinatorial chemistry , absorption (acoustics) , chemical engineering , ethylene oxide , stereochemistry , polymer , physics , quantum mechanics , acoustics , engineering , copolymer , thermodynamics
This study aims to synthesis of condensed and non‐condensed heterocyclic rings with long fatty chains as surface active biological compounds. 2‐Cyano‐3‐(dimethylamino)‐ N ‐octadecylacrylamide ( 5 ) was used to synthesize pyrimidine, pyran, and other condensed products by interacting with appropriate chemical reagents. These compounds were transferred to nonionic surface‐active agents by condensation with propylene oxide. The surface and biological properties showed that these compounds have a high solubility that helps them in easy absorption and adsorption with other compounds. In addition, they have a high ability to decrease the surface tension of the liquids, good wetting, and emulsification power, which can be used at different temperatures without losing their surface or biological properties and enable them for use in industrial and pharmaceutical purposes easily.