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An Efficient Five‐Component Reaction for the Synthesis of 4,4′‐((2‐Oxoindoline‐3,3‐diyl)bis(methylene))bis(2‐aryl‐1 H ‐pyrrolo[3,4‐ c ]quinoline‐1,3(2 H )‐dione) Derivatives
Author(s) -
Mao Kaimin,
Dai Lei,
Liu Yun,
Rong Liangce
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3592
Subject(s) - chemistry , quinoline , methylene , aryl , component (thermodynamics) , combinatorial chemistry , cascade reaction , cascade , medicinal chemistry , organic chemistry , catalysis , alkyl , physics , chromatography , thermodynamics
An efficient cascade process five‐component reaction of isatins and 3‐oxo‐ N ‐arylbutanamide for the synthesis of 4,4′‐((2‐oxoindoline‐3,3‐diyl)bis(methylene))bis(2‐aryl‐1 H ‐pyrrolo[3,4‐ c ]quinoline‐1,3(2 H )‐dione) derivatives was reported under mild condition. The advantages of this strategy are easy to obtain raw materials, convenient one‐pot procedure, and simple operation.