Synthesis of Hexahydrospiro[pyrazolo[3,4 ‐b ]quinoline‐4,1′‐pyrrolo[3,2,1‐ ij ]quinoline‐2′,5(1 H ,4′H)‐diones] from 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione Using Fe 3 O 4 @Cu(OH) x  as a Nanocatalyst | Zendy

Baradarani Mehdi M. | Zendy; Saatluo Bahman Ebrahimi | Zendy; Ghabeli Shiva | Zendy; Shokri Zahra | Zendy; Shahbazi Masoumeh | Zendy; Joule John A. | Zendy

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Synthesis of Hexahydrospiro[pyrazolo[3,4 ‐b ]quinoline‐4,1′‐pyrrolo[3,2,1‐ ij ]quinoline‐2′,5(1 H ,4′H)‐diones] from 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione Using Fe 3 O 4 @Cu(OH) x as a Nanocatalyst

Author(s) -

Baradarani Mehdi M.,

Saatluo Bahman Ebrahimi,

Ghabeli Shiva,

Shokri Zahra,

Shahbazi Masoumeh,

Joule John A.

Publication year - 2019

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.3579

Subject(s) - quinoline , chemistry , isatin , cyclohexane , benzopyran , tricyclic , stereochemistry , aryl , medicinal chemistry , condensation , ring (chemistry) , organic chemistry , physics , thermodynamics , alkyl

The tricyclic isatin, 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione, undergoes three‐component, one‐pot reactions with 1‐aryl‐3‐methylpyrazole‐5‐amines and cyclohexane‐1,3‐diones producing hexacyclic spiro products, hexahydrospiro[pyrazolo[3,4 ‐b ]quinoline‐4,1‐pyrrolo[3,2,1‐ ij ]quinoline‐2′,5(1 H ,4′H)‐diones]. Comparable spiro condensation products are also obtained using 4‐hydroxy‐2 H ‐1‐benzopyran‐2‐one in place of cyclohexane‐1,3‐diones.

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