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Synthesis of Hexahydrospiro[pyrazolo[3,4 ‐b ]quinoline‐4,1′‐pyrrolo[3,2,1‐ ij ]quinoline‐2′,5(1 H ,4′H)‐diones] from 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione Using Fe 3 O 4 @Cu(OH) x as a Nanocatalyst
Author(s) -
Baradarani Mehdi M.,
Saatluo Bahman Ebrahimi,
Ghabeli Shiva,
Shokri Zahra,
Shahbazi Masoumeh,
Joule John A.
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3579
Subject(s) - quinoline , chemistry , isatin , cyclohexane , benzopyran , tricyclic , stereochemistry , aryl , medicinal chemistry , condensation , ring (chemistry) , organic chemistry , physics , thermodynamics , alkyl
The tricyclic isatin, 5,6‐dihydro‐4 H ‐pyrrolo[3,2,1‐ ij ]quinoline‐1,2‐dione, undergoes three‐component, one‐pot reactions with 1‐aryl‐3‐methylpyrazole‐5‐amines and cyclohexane‐1,3‐diones producing hexacyclic spiro products, hexahydrospiro[pyrazolo[3,4 ‐b ]quinoline‐4,1‐pyrrolo[3,2,1‐ ij ]quinoline‐2′,5(1 H ,4′H)‐diones]. Comparable spiro condensation products are also obtained using 4‐hydroxy‐2 H ‐1‐benzopyran‐2‐one in place of cyclohexane‐1,3‐diones.