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An Eco‐friendly Catalytic System for One‐pot Multicomponent Synthesis of Diverse and Densely Functionalized Pyranopyrazole and Benzochromene Derivatives
Author(s) -
Patil U. P.,
Patil Rupesh C.,
Patil Suresh S.
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3564
Subject(s) - chemistry , environmentally friendly , catalysis , yield (engineering) , organic chemistry , combinatorial chemistry , one pot synthesis , chemical engineering , ecology , materials science , metallurgy , biology , engineering
An external base‐free, efficient, cost‐effective, and environmentally benign protocol has been developed for the one‐pot multicomponent synthesis of highly functionalized pyranopyrazoles and benzochromenes using water extract of Agave americana (century plant) leaf ash, a waste‐derived catalyst, at room temperature. Mild reaction conditions, high yield, easy isolation of products, eco‐friendly standards, and no chromatographic separation are the salient features of this protocol.