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Synthesis of imidazo[1,2‐ c ]quinazolin‐5(6 H )‐ones and benzimidazo[1,2‐ c ]quinazolin‐6(5 H )‐ones with the aid of low‐valent titanium reagent
Author(s) -
Zhao Xuan,
Shi DaQing
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.353
Subject(s) - chemistry , reagent , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
A short and facile synthesis of imidazo[1,2‐ c ]quinazolin‐5(6 H )‐ones and benzimidazo[1,2‐ c ]quinazolin‐6(5 H )‐ones was accomplished in good yields via the novel reductive cyclization of 2‐(2‐nitrophenyl)imidazoles or 2‐(2‐nitrophenyl)benzoimidazoles with isocyanates promoted by low‐valent titanium reagent. J. Heterocyclic Chem., (2010).