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Solvent Free Synthesis of N‐Substituted Pyrroles Catalyzed by Calcium Nitrate
Author(s) -
Wani Rucha R.,
Chaudhari Hemchandra K.,
Takale Balaram S.
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3507
Subject(s) - chemistry , catalysis , reaction conditions , pyrrole , solvent , nitrate , organic chemistry , calcium nitrate , calcium , combinatorial chemistry
Moderated and mild way for synthesizing N‐substituted pyrrole has been demonstrated herein. No solvents need to be used for this reaction, and instead, reactants themselves acted as a reaction medium. In fact, the reaction is carried out using catalytic amount of Ca(NO 3 ) 2 .4H 2 O. The reaction conditions are selective and mild that helped to tolerate a wide variety of functional groups to give the desired products in good chemical yields.