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Synthesis and Insecticidal Evaluation of Novel N ‐pyridylpyrazole Derivatives Containing Diacylhydrazine/1,3,4‐Oxadiazole Moieties
Author(s) -
Wang Wei,
Zheng XiaoRui,
Huang XiaoYing,
Mao MingZhen,
Liu KangYun,
Xue Chao,
Wang LiePing,
Ning BinKe
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3505
Subject(s) - mythimna separata , plutella , chemistry , oxadiazole , bioassay , proton nmr , stereochemistry , combinatorial chemistry , organic chemistry , lepidoptera genitalia , ecology , genetics , biology
Two series of novel N ‐pyridylpyrazole derivatives containing diacylhydrazine/1,3,4‐oxadiazole moieties were designed and synthesized based on the structure of chlorantraniliprole and characterized via 1 H‐NMR, 13 C‐NMR, IR, MS, and elemental analysis. The preliminary bioassay indicated that some of the title compounds I and II exhibited larvicidal activities against Mythimna separata with 90–100% death rates at 500 mg/L. The further test showed that these compounds had weak insecticidal activity against Mythimna separata and Plutella xylostella at 200 mg/L and might be not suitable as insecticide lead compound for further optimization.