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Synthesis of novel 2,3‐dihydro‐3‐hydroperoxy‐2‐aryl‐4,5‐diphenylisothiazole 1,1‐dioxides and their epoxidation ability
Author(s) -
Makota Oksana,
Wolf Janine,
Trach Yuriy,
Schulze Barbel
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.350
Subject(s) - chemistry , cyclooctene , aryl , catalysis , medicinal chemistry , organic chemistry , alkyl
AbstractThe novel hydroperoxy sultams, 2,3‐dihydro‐3‐hydroperoxy‐2‐aryl‐4,5‐diphenylisothiazole 1,1‐dioxides, were synthesized by the oxidation of the 2‐aryl‐4,5‐diphenyl substituted isothiazolium salts with H 2 O 2 . These hydroperoxy sultams were investigated as epoxidation agents in the epoxidation reaction of cis ‐cyclooctene catalyzed by MoB. 2‐(2‐Chlorophenyl)‐2,3‐dihydro‐3‐hydroperoxy‐4,5‐diphenylisothiazole 1,1‐dioxide was found to have the highest epoxidation ability. J. Heterocyclic Chem., (2010).