Premium
Solvent‐free chemoselective synthesis of some novel substituted 2‐arylbenzimidazoles using amino acid‐based prolinium nitrate ionic liquid as catalyst
Author(s) -
Rostamizadeh Shahnaz,
Aryan Reza,
Ghaieni Hamid Reza,
Amani Ali Mohammad
Publication year - 2009
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.35
Subject(s) - ionic liquid , chemistry , chemoselectivity , catalysis , solvent , nitrate , organic chemistry , environmentally friendly , combinatorial chemistry , ionic bonding , ion , ecology , biology
A simple and eco‐friendly protocol for the synthesis of substituted 2‐arylbenzimidazoles is described. In this process, 2‐arylbenzimidazoles were prepared in the presence of a newly introduced ionic liquid prolinium nitrate [Pro]NO 3 as catalyst, under solvent‐free condition. This process was performed under mild condition without using any oxidant with good to excellent yields and remarkable chemoselectivity in the absence of any byproduct. The ionic liquid can be recovered easily and reused. J. Heterocyclic Chem., 46 , 74 (2009).