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Synthesis and Reactions of a New Quinone Quinoline 7‐(Carboxymethoxy)‐3‐sulfoquinoline‐5,6‐dione
Author(s) -
Dinh Nguyen Huu,
Len Vu Thi,
Hang Bui Thi Yen,
Hoa Le Thi
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3490
Subject(s) - chemistry , quinoline , phenylhydrazine , hydroxylamine , hydrazine (antidepressant) , semicarbazide , quinone , medicinal chemistry , ethylenediamine , isatin , ethanol , proton nmr , organic chemistry , chromatography
The new ortho ‐quinone quinoline 7‐(carboxymethoxy)‐3‐sulfoquinoline‐5,6‐dione was synthesized. The reaction of this quinoline‐5,6‐dione with hydroxylamine, hydrazine, phenylhydrazine, ethanol, semicarbazide, thiosemicarbazide, ethylenediamine, and benzene‐1,2‐diamine were studied. Ten new azaheterocyclic compounds were isolated and characterized by elemental analyses, IR, 1D NMR, 2D NMR, and MS spectra. Antioxidant activities of some obtained compounds were tested.