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The Novel Synthesis of Functionalized Indenopyrazolones Using Fe 3 O 4 nanoparticles stabilized on MMT: An Efficient Magnetically Recoverable Heterogeneous Nanocomposite Catalyst
Author(s) -
Hosseini Nasab Narges,
Safari Javad
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3469
Subject(s) - catalysis , phenylhydrazine , chemistry , nanocomposite , reusability , environmentally friendly , chemical engineering , heterogeneous catalysis , condensation , ninhydrin , nanoparticle , combinatorial chemistry , organic chemistry , ecology , biochemistry , physics , thermodynamics , software , amino acid , computer science , engineering , biology , programming language
A practical and simple approach for the one‐pot multicomponent synthesis of indenopyrazolones is described via the condensation of ninhydrin (indan‐1,2,3‐trione), phenylhydrazine, and various aldehydes in the presence of MMT@Fe 3 O 4 as an environmentally benign core/shell nanocomposite catalyst. The catalyst could be recycled using an external magnet easily and reused several times without remarkable loss of its catalytic activity. Furthermore, avoiding hazardous solvents, reusability of the catalyst, easy work‐up, short reaction times, room temperature, and mild reaction conditions are the advantages of this new eco‐friendly protocol.