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Multicomponent Efficient Synthesis of New [1,2,4]Triazolo[3,4]thiadiazines
Author(s) -
Sujatha Kodam,
Vedula Rajeswar Rao
Publication year - 2019
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3458
Subject(s) - chemistry , phenacyl , 1,2,4 triazole , condensation , combinatorial chemistry , proton nmr , organic chemistry , thermodynamics , physics
A series of novel triazolo thiadiazines were synthesized by a simple, highly efficient, one‐pot pseudo four component approach involving the condensation of 4‐amino‐5‐hydrazinyl‐4 H ‐1,2,4‐triazole‐3‐thiol ( 1 ), aromatic aldehydes ( 2 ), and various phenacyl bromides ( 3 ) with good yields. The structures of compounds were confirmed by analytical and spectral (IR, 1 H NMR, 13 C NMR) data.