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Tandem Michael addition/imino‐nitrile cyclization synthesis of 2‐amino‐6‐(1‐aryl‐5‐methyl‐1 H ‐1,2,3‐triazol‐4yl)‐4‐phenylpyridine‐3‐carbonitrile
Author(s) -
Dong HengShan,
Wang HuiCheng,
Gao ZhongLian,
Li RongShan,
Cui FuHong
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.336
Subject(s) - chemistry , nitrile , tandem , aryl , crystal structure , michael reaction , proton nmr , stereochemistry , medicinal chemistry , organic chemistry , catalysis , alkyl , materials science , composite material
everal 2–amino‐6‐(1‐aryl‐5‐methyl‐1 H ‐1,2,3‐triazol‐4‐yl)‐4‐phenylpyridine‐3‐carbonitrile have been synthesized by Tandem Michael addition/imino‐nitrile cyclization and the structures of these compounds were established by MS, IR, CHN, and 1 H NMR spectral data. The crystal structure of 2‐amino‐6‐[1‐(4‐methoxyphenyl)‐5‐methyl‐1 H ‐1,2,3‐triazol‐4‐yl]‐4‐phenylpyridine‐3‐carbonitrile was established by X‐ray diffraction. J. Heterocyclic Chem., (2010).