Premium
Microwave‐assisted Synthesis of Dihydro Dibenzophenanthroline and Its Derivatives Using a Self‐catalyzed Friedlander Reaction
Author(s) -
Chandraprakash Kumarasamy,
Vandandakumar,
Sankaran Mathan,
Uvarani Chokkalingam,
Ata Athar,
Mohan Palathurai Subramaniam,
Suresh Thangaraj
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3339
Subject(s) - chemistry , benzophenone , catalysis , yield (engineering) , microwave irradiation , solvent , microwave , combinatorial chemistry , ring (chemistry) , organic chemistry , reaction conditions , thin layer chromatography , photochemistry , materials science , physics , quantum mechanics , metallurgy
One‐step microwave‐assisted synthesis of dihydro dibenzophenanthrolines are reported using a self‐catalyzed Friedlander reaction. The reaction is carried out in one step by simple microwave irradiation of 3,4‐dihydroacridin‐1(2 H )‐one with 2‐amino‐benzophenone in the presence of acid catalysts with solvent‐free conditions. Thin‐layer chromatography was used to monitor the progress of the reaction; hence, it was observed that the reaction starts slowly and accelerates as it proceeds to ring fusion transformation. Synthesized compounds' isolated yield is enhanced in the absence of solvent systems with Friedlander catalyst under microwave irradiations.