A Simple One‐pot Three‐component Synthesis of Dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazol‐3‐ols by Reaction of Acyl Chlorides, Isocyanides, and 2‐Mercaptobenzimidazoles | Zendy

Talebizadeh Mahdiyeh | Zendy; AnaryAbbasinejad Mohammad | Zendy; Darehkordi Ali | Zendy

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A Simple One‐pot Three‐component Synthesis of Dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazol‐3‐ols by Reaction of Acyl Chlorides, Isocyanides, and 2‐Mercaptobenzimidazoles

Author(s) -

Talebizadeh Mahdiyeh,

AnaryAbbasinejad Mohammad,

Darehkordi Ali

Publication year - 2018

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.3335

Subject(s) - chemistry , isocyanide , yield (engineering) , adduct , medicinal chemistry , combinatorial chemistry , component (thermodynamics) , chloride , reaction conditions , organic chemistry , catalysis , physics , thermodynamics , materials science , metallurgy

The reactive imidoyl chloride adducts generated in situ from the reaction of isocyanide and acyl chlorides were trapped by 2‐mercaptobenzimidazole to yield highly functionalized dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazoles in excellent yields.

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