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A Simple One‐pot Three‐component Synthesis of Dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazol‐3‐ols by Reaction of Acyl Chlorides, Isocyanides, and 2‐Mercaptobenzimidazoles
Author(s) -
Talebizadeh Mahdiyeh,
AnaryAbbasinejad Mohammad,
Darehkordi Ali
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3335
Subject(s) - chemistry , isocyanide , yield (engineering) , adduct , medicinal chemistry , combinatorial chemistry , component (thermodynamics) , chloride , reaction conditions , organic chemistry , catalysis , physics , thermodynamics , materials science , metallurgy
The reactive imidoyl chloride adducts generated in situ from the reaction of isocyanide and acyl chlorides were trapped by 2‐mercaptobenzimidazole to yield highly functionalized dihydrobenzo[4,5]imidazo[2,1‐ b ]thiazoles in excellent yields.