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Synthesis of Spiro[indoline‐3,4′‐pyrano[3,2‐ c ]chromene]diones
Author(s) -
Ghadiri Sakineh,
Bayat Mohammad,
Hosseini Fahimeh Sadat
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3326
Subject(s) - isatin , chemistry , indoline , catalysis , alkyl , organic chemistry , ethanol , solvent , combinatorial chemistry
A new series of isatin‐based spiro‐fused derivatives were prepared, via three‐component reaction of N‐ alkyl‐1‐(methylthio)‐2‐nitroethenamine derived from the addition of various amines to nitroketene dithioacetal with isatin derivatives and 4‐hydroxycoumarin in ethanol as a solvent at reflux. The significant advantages of this protocol include simple operation under mild conditions, easy purification, good yields, and catalyst‐free approach.