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An Efficient, Green, and Solvent‐free Multi‐component Synthesis of Benzimidazolo/Benzothiazolo Quinazolinone Derivatives Using Sc (OTf) 3 Catalyst Under Controlled Microwave Irradiation
Author(s) -
Gajaganti Somaiah,
Kumari Savita,
Kumar Dhirendra,
Allam Bharat Kumar,
Srivastava Vandana,
Singh Sundaram
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3314
Subject(s) - chemistry , quinazolinone , catalysis , microwave irradiation , trifluoromethanesulfonate , organic chemistry , scandium , solvent , component (thermodynamics) , microwave , reaction conditions , combinatorial chemistry , physics , quantum mechanics , thermodynamics
An efficient, fast, and green synthesis of benzimidazolo/benzothiazolo quinazolinone derivatives has been developed under solvent‐free conditions by the reaction of 2‐aminobenzimidazole/2‐aminobenzothiazole, aromatic aldehydes, and 1,3‐diketones. This method extended the application of microwave irradiation and scandium triflate combination and also tenders a lot of benefits such as excellent product yields, shorter reaction time, easy isolation of products, and environmentally benign reaction conditions.