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SnCl 2 · 2H 2 O‐catalyzed one‐pot synthesis of 4(3 H )‐quinazolinones from anthranilic acid, ortho esters, and amines under solvent free conditions
Author(s) -
Wang Min,
Song Zhiguo,
Zhang Tingting
Publication year - 2010
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.330
Subject(s) - chemistry , anthranilic acid , catalysis , condensation , solvent , organic chemistry , medicinal chemistry , reaction conditions , physics , thermodynamics
A simple, efficient, and green procedure for the one‐pot synthesis of 4(3 H )‐quinazolinones by three components condensation of anthranilic acid, ortho esters, and amines in the presence of SnCl 2 · 2H 2 O has been developed. The reaction occurred within short reaction time at room temperature under solvent‐free conditions to afford the title products in excellent yields. J. Heterocyclic Chem., (2010).