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Synthesis and Antioxidant Activity of Bis (Aroyl/Arylsulfonyl Ethenesulfonylmethylazolyl)Pyridines
Author(s) -
Gunthanakkala Anil Kumar,
Mangali Madhusekhar,
Gudi Yamini,
Tatha Sreenivasulu,
Venkatapuram Padmavathi,
Adivireddy Padmaja
Publication year - 2018
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.3259
Subject(s) - chemistry , pyridine , antioxidant , sonication , thiadiazoles , organic chemistry , medicinal chemistry , combinatorial chemistry , chromatography
A new class of 2,6‐pyridine linked bis (oxadiazoles), bis (thiadiazoles), and bis (triazoles) were prepared from the synthetic intermediates pyridine‐2,6‐dicarbohydrazide, E ‐aroylethenesulfonylacetic acid and E ‐arylsulfonylethenesulfonylacetic acid adopting ultrasonication methodology and tested for their antioxidant activity. Among all the tested compounds 2,6‐(bis (2‐(4‐methylbenzoylethenesulfonylmethyl)‐1,3,4‐oxadiazol‐5‐yl))‐pyridine ( 7b ) was found to be potential antioxidant agent.